High severity · published May 20, 2026
CVE-2026-45498
Microsoft Defender Denial of Service Vulnerability
In wildKEV
7.5
CVSS
63.1%
EPSS
Yes
On KEV
CVSS vector
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H
Attack vector
Network
Complexity
Low
Privileges
None
User interaction
None
Confidentiality
None
Integrity
None
Availability
High
Scope
Unchanged
Exploitation
Is it being used?
Exploit prediction (EPSS)63.1% · higher than 99% of CVEs
Exploited in the wildYes
CISA KEVListed May 20, 2026
Federal remediation dueJun 3, 2026
Ransomware campaign useNot known
Affected products
Which versions
MD
Microsoft Defender Antimalware Platform · Microsoft
4.0.0.0 before 4.18.26040.7 · source: vendor
DA
Defender Antimalware Platform · Microsoft
before 4.18.26040.7 · source: NVD
DE
Defender · Microsoft
All versions, or not specified · source: KEV
In the news
VulnerabilityCritical
Microsoft Defender vulnerabilities exploited in the wild (CVE-2026-41091, CVE-2026-45498)
Attackers are exploiting two Microsoft Defender vulnerabilities (CVE-2026-41091 and CVE-2026-45498), Microsoft acknowledged and CISA confirmed by adding them to its Known Exploited Vulnerabilities catalog. The vulnerabilities CVE-2026-41091 allows for local privilege elevation (LPE), and is caused by the Microsoft Malware Protection Engine improperly resolving links before accessing files. “An attacker who successfully exploited this vulnerability could gain SYSTEM privileges,” Microsoft noted. CVE-2026-45498 can cause a denial-of-service (DoS) state, i.e., it can be used to prevent … More →
The post Microsoft Defender vulnerabilities exploited in the wild (CVE-2026-41091, CVE-2026-45498) appeared first on Help Net Security .
May 21, 2026·Help Net Security
AdvisoryHigh
CISA Adds Seven Known Exploited Vulnerabilities to Catalog
CISA has added seven new vulnerabilities to its Known Exploited Vulnerabilities (KEV) Catalog , based on evidence of active exploitation.
CVE-2008-4250 Microsoft Windows Buffer Overflow Vulnerability
CVE-2009-1537 Microsoft DirectX NULL Byte Overwrite Vulnerability
CVE-2009-3459 Adobe Acrobat and Reader Heap-Based Buffer Overflow Vulnerability
CVE-2010-0249 Microsoft Internet Explorer Use-After-Free Vulnerability
CVE-2010-0806 Microsoft Internet Explorer Use-After-Free Vulnerability
CVE-2026-41091 Microsoft Defender Elevation of Privilege Vulnerability
CVE-2026-45498 Microsoft Defender Denial of Service Vulnerability
These types of vulnerabilities are frequent attack vectors for malicious cyber actors and pose significant risks to the federal enterprise.
Binding Operational Directive (BOD) 22-01: Reducing the Significant Risk of Known Exploited Vulnerabilities established the KEV Catalog as a living list of known Common Vulnerabilities and Exposures (CVEs) that carry significant risk to the federal enterprise. BOD 22-01 requires Federal Civilian Executive Branch (FCEB) agencies to remediate identified vulnerabilities by the due date to protect FCEB networks against active threats. See the BOD 22-01 Fact Sheet for more information.
Although BOD 22-01 only applies to FCEB agencies, CISA strongly urges all organizations to reduce their exposure to cyberattacks by prioritizing timely remediation of KEV Catalog vulnerabilities as part o...
May 20, 2026·CISA Advisories
VulnerabilityHigh
[CISA KEV] CVE-2026-45498: Microsoft Defender - Microsoft Defender Denial of Service Vulnerability
Microsoft Defender contains an unspecified vulnerability that allows for denial of service.
DEDefenderCVE-2026-45498
May 20, 2026·CISA KEV
Affected product
MD
Microsoft Defender Antimalware Platform
Microsoft
References
NVD
https://nvd.nist.gov/vuln/detail/CVE-2026-45498
CVE.org
https://www.cve.org/CVERecord?id=CVE-2026-45498
CISA KEV catalogue
https://www.cisa.gov/known-exploited-vulnerabilities-catalog
vendor-advisory
https://msrc.microsoft.com/update-guide/vulnerability/CVE-2026-45498
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