High severity · published Sep 27, 2026
CVE-2026-100846
MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization
8.8
CVSS
0.4%
EPSS
No
On KEV
Description
MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.
CVSS vector
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Attack vector
Network
Complexity
Low
Privileges
None
User interaction
Required
Confidentiality
High
Integrity
High
Availability
High
Scope
Unchanged
Exploitation
Is it being used?
Exploit prediction (EPSS)0.4% · higher than 30% of CVEs
Exploited in the wildNo evidence yet
CISA KEVNot listed
Ransomware campaign useNot known
Affected products
Which versions
MO
MONAI · Project-MONAI
before 1.5.2 · source: vendor, NVD
References
NVD
https://nvd.nist.gov/vuln/detail/CVE-2026-100846
CVE.org
https://www.cve.org/CVERecord?id=CVE-2026-100846
vendor-advisory
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4
third-party-advisory
https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization
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